Papers

2005


• E. Skrzypczak-Jankun, O. Borbulevych, A. Melillo, R. Keck, M. Soriano-Garcia, J. Aniola, L. Lilge, M. Niedre, S. H. Selman, J. Jankun. Aspirin Blocks Binding of Photosensitizer SnET2 into Human Serum Albumin; Implications for Photodynamic Therapy.International Journal of Molecular Medicine, 15 (5): 777-783, 2005, full paper in pdf.

2004

• Miocinovic, R., McCabe, N. P., Keck, R. W., Jankun, J., Hampton, J. A., Selman, S. H. In vivo and in vitro effect of baicalein on human prostate cancer cells, International Journal of Oncology, 26 (1), 241-246, 2005. full paper in pdf.

• Jankun, J., Lilge, L., Douplik, A., Keck, R. W., Pestka, M., Szkudlarek, M., Stevens, P. J., Lee, R. J., Selman, S. H. Optical characteristics of the canine prostate at 665 nm sensitized with tin etiopurpurin dichloride: need for real-time monitoring of photodynamic therapy. The Journal of Urology, 172: 2, 739-743, 2004, full paper in pdf.

• Lothar Lilge, Natalie Pomerleau-Dalcourt, Alexander Douplik,
  Steven H Selman, RickW Keck, Maria Szkudlarek, Maciej Pestka
  and Jerzy Jankun. Transperineal in vivo fluence-rate dosimetry in the
  canine prostate during SnET2-mediated PDT, Physics in Medicine and Biology, 49, 3209–3225, 2004, full paper in pdf.

• Skrzypczak-Jankun, E., Borbulevych, O. Y., Jankun, J. Soybean lipoxygenase-3 in complex with 4-nitrocatechol. Acta Crystallogr D Biol Crystallogr, 60:Pt3, 613-615, 2004.

• Borbulevych, O. Y., Jankun J., Selman S. H., Skrzypczak-Jankun, E. Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X-ray structure at 2.1 Å resolution. Proteins: Structure, Function and Genetics 54(1): 13-19, 2004.
  
• Joanna Chorostowska-Wynimko, Ewa Skrzypczak-Jankun, Jerzy Jankun. Plasminogen activator inhibitor type-1: its structure, biological activity and role in tumorigenesis. Int. J. Molecular Medicine - accepted 2/2004, preprint, full paper in PDF.
  
  
• Ewa Skrzypczak-Jankun, Oleg Y. Borbulevych, Jerzy Jankun. Soybean lipoxygenase-3 in complex with 4-nitrocatechol. Acta Cryst. D - accepted 1/2004
  
  2003
  
  
• Jankun, J, Skrzypczak-Jankun, E, Zhou, K. Inhibition of lipoxygenase by (-)-epigallocatechin gallate: X-ray analysis at 2.1 Å reveals degradation of EGCG and shows soybean LOX-3 complex with EGC instead. International Journal of Molecular Medicine, accepted, 2003, preprint, full paper in PDF.
  
  
• Jankun, J, Skrzypczak-Jankun, E, Zhou, K, Selman, H. S., McCabe, P. N. Structure of curcumin in complex with lipoxygenase and its significance in cancer.International Journal of Molecular Medicine, accepted, 2003, preprint, full paper in PDF.
  
  
• Wojtowicz, A., Selman, SH., Jankun, J. Computer Simulation of Prostate Cryoablation - Fast Approximation of Exact Solution, Computer Aided Surgery, 8: 91-97, 2003.
  
  
• Jankun, J., Selman, S. H., Skrzypczak-Jankun, E. Control of the aggressive capacity of prostate cancer by nutritional inhibitors of urokinase and lipoxygenase, Int. J. Hum. Genet. 3(2):127-134, 2003.
  
  
• Kemberling, J.K., Hampton, J.A., Keck, R.W., Gomez, M.A., and Selman, S.H. Inhibition of Bladder Tumor Growth by the Green Tea Derivative Epigallocatechin-3-Gallate, Journal of Urology Vol. 170, 773-776, 2003.
  
  
• Chorostowska-Wynimko, J., Swiercz, R., Skrzypczak-Jankun, E., Wojtowicz, A., Selman, S. H., and Jankun, J. Novel Forms of Plasminogen Activator Inhibitor (PAI-1) Created by Cysteine Mutations Extends Half-life; Relevance in Cancer and Angiogenesis, Molecular Cancer Therapeutics, invited paper, 2: 19-28, 2003.
  
  
• Aniola, J. Selman, S. H., Keck, R., Jankun, J., Spatial distribution of liposome encapsulated tin etiopurpurin dichloride (SnET2) in the canine prostate; Implications for computer simulation of photodynamic therapy. International Journal of Molecular Medicine 11: 287-291, 2003.
  
  2002
  
  
• Gong, B., Zeng, H., Zhu, J., Yua, L., Han, Y., Cheng, S., Furukawa, M., Parra, R. D., Kovalevsky, A. Y., Mills, J. L., Skrzypczak-Jankun, E., Martinovic, S., Smith, R. D., Zheng, C., Szyperski, T., Zeng, X. Ch. Creating nanocavities of tunable sizes: Hollow helices. Proc. Natl. Acad. Sci.USA 99, 11583-11588, 2002.
  
  2001
  
  
• Jankun, J, Skrzypczak-Jankun, E. Binding site of amiloride to urokinase plasminogen activator depends on species. International Journal of Molecular Medicine, accepted, 2001, preprint, full paper in PDF.
  
  
• Swiercz, R., Keck, R. W., Skrzypczak-Jankun, E., S, Selman, H. S., and Jankun, J. Recombinant PAI-1 inhibits angiogenesis and reduces size of LNCaP prostate cancer xenografts in SCID mice, Oncology Reports, 8: 463-470, 2001, full paper in PDF.
  
  
• Zaim, A., Keck, R. W., Selman, S. H., Jankun, J. Two-dimensional Ultrasound Image Matching System for Photodynamic Therapy, Proceedings of BIOS-SPIE, 4244: 327-337, 2001.
  
  
• Selman, S., Albrecht, D., Keck, R., Brennan, P., and Kondo, S.; Studies of Tin Ethyl Etiopurpurin Photodynamic Therapy of the Canine Prostate. J. Urology, 165: 1795-1801, 2001.
  
  
• Selman, S.H., Sindhwani, P., Hampton, J.A., Baig, M.M., and Keck, R. Curcumin prevents Intravesical Tumor Implantation of the MBT-2 Tumor Cell Line in C3H Mice. J. Urology, 166: 1498-1501, 2001.
  
  
• Selman, S.H., McDonough, M.J., Feldmeier, J.J., Parsai, I., Dobelbower, R.R., Jr.: Salvage External Beam Radiotherapy for Clinical Failure after Cryosurgery for Prostate Cancer. Int. J. Radiation Oncology Biol. Phys, 51: (3), 624-627, 2001.
  
  
• Bhamidi, V., Skrzypczak-Jankun, E., Schall, C. A. Dependence of nucleation kinetics and crystal morphology of a model protein system on ionic strength. J.Crystal Growth 232, 77-85, 2001.
  
  
• Skrzypczak-Jankun, E., Bross, R., Carroll, R. T., Dunham, W. R., Funk Jr, M. O. Three dimensional structure of a purple lipoxygenase. J. Am. Chem. Soc. 123, 10814-10820, 2001.
  
  2000
  
  
• Skrzypczak-Jankun, E., McCabe, P. N., Selman, S. H., and Jankun, J. Curcumin Inhibits Lipoxygenase by Binding to its Central Cavity: Theoretical and X-ray Evidence. International Journal of Molecular Medicine, 6: 521-526, 2000, full paper in PDF.
  
  
• McCabe, N.P, Angwafo, F. III, Zaher, A., Selman SH, Kouanche A, and Jankun J. Expression of Soluble Urokinase Plasminogen Activator Receptor May be Related to Outcome in Prostate Cancer Patients, Oncology Reports, 7: 879-882, 2000, full paper in PDF.
  
  
• Jankun, J., Zaim, A., Jankun-Kelly, M., Keck, R. W. and Selman, S. H. Computer Model for Photodynamic Therapy of the Prostate. Proceedings of SPIE, 3907: 222-228, 2000.
  
  
• Selman, S. "LATENT" Carcinoma of the Prostate: A Medical Misnomer? Urology, 56: 708-711, 2000.
  
  
• Selman, S. H. , Sindhwani, P., Hampton, J.A., Keck, R.W., and Baig, M.M. Curcumin: A Food Spice with Cytotoxic activity against Urinary Bladder Cancer. SURGICAL FORUM, 625-626, 2000.
  
  
• Kwok, W. H., Zhang, H., Payra, P., Duan, M., Hung, S., Johnston, D. H., Gallucci, J., Skrzypczak-Jankun, E., Chan, M. K. Synthesis and Characterization of the Dimethyl-substituted Bisbenzimidazole Ligand and Its Manganese Complex. Inorganic Chemistry 39, 2367-2376, 2000.
  
  
• Macikenas, D., Skrzypczak-Jankun, E., Protasiewicz, J. Redirecting Secondary Bonds to Control Molecular and Crystal Properties of an Iodosylbenzene and an Iodoxybenzene. Angew. Chem. 39, 2007-2010, 2000.
  
  
• Zhu, J., Parra, R. D., Zeng, H., Skrzypczak-Jankun, E., Zeng, X, Ch., Gong, B. A Novel Class of Folding Oligomers: Crescent Oligoamides. J. Am. Chem. Soc. 122, 4219-4220, 2000.
  
  
• Gong, B., Zheng, C., Skrzypczak-Jankun, E., Zhu, J. Two-dimensional molecular layers: Interplay of H-bonding and van der Waals interactions in the self-assembly of N,N'-dialkylsulfamides. Organic Letters 2, 3273-3275, 2000.
  
  1999
  
  
• Jankun, M., T.J. Kelly, Zaim, A. Young, K., Keck, R. W., Selman, S. H., and J Jankun. Computer Model for Cryosurgery of the Prostate, Computer Aided Surgery, 4: 193-199, 1999.
  
  
• Swiercz R, Skrzypczak-Jankun E, Merrell M M, Selman H S, Jankun J. Angiostatic Activity of Synthetic Inhibitors of Urokinase Type Plasminogen Activator, Oncology Reports, 6: 523-536, 1999 full paper in PDF. Abstract.
  
  
• B. Bhamidi, B. L. Hanson, A. Edmundson, E. Skrzypczak-Jankun, C. Schall. Effect of Protein Impurity on HEWL Crystal Growth. J. Crystal Growth 204, 542-552, 1999.
  
  
• Jankun J, Skrzypczak-Jankun, E. Molecular Basis of Specific Inhibition of Urokinase Plasminogen Activator by Amiloride, Cancer Biochemistry Biophysics, 17; 1-2, 109-123, 1999.
  
  
• Macikenas, D., Skrzypczak-Jankun, E., Protasiewicz, J. A New Class of Iodonium Ylides Engineered as Soluble Primary Oxo and Nitrene Sources. J. Am. Chem. Soc. 121, 7164-7165, 1999.
  
  
• Gong, B.,Yan, Y.,Zeng, H., Skrzypczak-Jankun, E., Kim, J. W., Zhu, J., Ickes, H. A New Approach for the Design of Supramolecular Recognition Units: Hydrogen-Bonded Molecular Duplexes. J.Am.Chem.Soc. 121, 5607-5608, 1999.
  
  1998
  
  
• Swiercz, R., Wolfe, J. D., Zaher, A., Jankun, J. Expression of The Plasminogen Activation System In Kidney Cancer Correlates With its Aggressive Phenotype. Clinical Cancer Research, April, 1998.
  
  
• Pham C., Jankun, J., Skrzypczak-Jankun, E., Flowers II, R. A., Funk, M. O. Jr. Structural and Thermochemical Characterization of Lipoxygenase Catechol Complexes. Biochemistry, 37:51, 17952-17957, 1998.
  
  
• Gong, B., Zheng, C., Skrzypczak-Jankun, E., Yan, Y., Zhang, J. A Robust Two-Dimensional Supramolecular Module: The Sulfamide Moiety as a New Building Block for the Design and Self-Assembly of Molecular Solids. J.Am. Chem.Soc. 120, 11194-11195, 1998.
  
  
• Grafstein, L.A., Selman, S. H..:Thermal Lasers in Urologic Oncology. Journal of Clinical Laser Medicine & Surgery, 16 (1) 49-54, 1998.
  
  1997
  
  
• Jankun, J., Swiercz, R., Selman, S. H., Skrzypczak-Jankun, E. Why Drinking Green Tea Could Prevent Cancer. Nature, 387, 561, 1997.